bs-42250P-APC

DATASHEET

Entrez Gene: 54664

Swiss Prot: Q9NUM4

Source: Recombinant human TMEM106B protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 2-96/274

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

TMEM106B is a 274 amino acid single-pass membrane protein that is encoded by a gene which maps to human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100ug,500ug,20ug

Applications: Others()

Mol. Wt.: 28.6

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.