DATASHEET
Entrez Gene:
13614
Swiss Prot:
P22387
Source:
Recombinant mouse Endothelin-1 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 426-202/202
Storage Buffer:
20mM Tris-HCl (pH8.0) with 2M Urea.
Storage:
The product should be stored at -70°C or -20°C.
Background:
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Molecular weight: 2491.9
Molecular formula: C109H159N25O32S5
CAS: 117399-94-7
MDL: MFCD00133305
Reconstitution: 1mM (1mg/0.4013mL)
Sequence:
26-202/202