bs-42259P

DATASHEET

Entrez Gene: 7350

Swiss Prot: P25874

Source: Recombinant human UCP1 protein is expressed in E.coli with His. It contains the amino acid sequence of 1-307/307

Storage Buffer: 20mM Tris-HCl (pH8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq].

Sequence: 1-307/307

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 36.2

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.