bs-42274P

DATASHEET

Entrez Gene: 3683

Swiss Prot: P20701

Source: Recombinant human CD11a protein is expressed in E.coli with N-His. It contains the amino acid sequence of 26-350/1086

Storage Buffer: 20mM Tris-HCl (pH8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Sequence: 26-350/1086

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 39

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.