bs-42280P-APC

DATASHEET

Entrez Gene: 10891

Swiss Prot: Q9UBK2

Source: Recombinant human PPARGC1A is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 11-280/798

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100ug,500ug,20ug

Applications: Others()

Mol. Wt.: 47.8

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.