bs-42281P-Biotin

DATASHEET

Entrez Gene: 9076

Swiss Prot: O88551

Source: Recombinant mouse CLDN1 protein is is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 137-211/211

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]

Sequence: 137-211/211

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µg, 500µg, 20µg

Applications: Others

Predicted Molecular Weight: 26.4

Cross Reactive Species: Others

For research use only. Not intended for diagnostic or therapeutic use.