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Host: Rabbit
Target Protein: IL18
Immunogen Range: 37-193/193
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 29197
Swiss Prot: P97636
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
| IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. |
Size: 100µL
Concentration: 1ug/ul
Applications: WB(1:300-5000)
Predicted Molecular Weight: 22
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.
Lane 1: Human HeLa cell lysates; Lane 2: HeLa treated with Brefeldin A( 5 μg/ml，15 min); Lane 3: Human Jurkat cell lysates(Negative control) probed with IL18 Polyclonal Antibody, Unconjugated (bs-42309R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.