bs-42311P

DATASHEET

Entrez Gene: 1582

Swiss Prot: Q9UNU6

Source: Recombinant human CYP8B1 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 22-501/501

Storage Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea and 0.5M L-Arg.

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]

Sequence: 22-501/501

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 59.5

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.