bs-42312P

DATASHEET

Entrez Gene: 5159

Swiss Prot: P09619

Source: Recombinant human PDGFRB protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 696-1106/1106

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].

Sequence: 696-1106/1106

Size: 100ug, 500ug, 20ug

Applications: Others

Mol. Wt.: 64.2

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.