bs-42318P

DATASHEET

Entrez Gene: 2833

Swiss Prot: P49682

Source: Recombinant human CXCR3 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 1-53/368

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011].

Size: 100ug,500ug,20ug

Applications: Others()

Mol. Wt.: 24

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.