bs-42318P-APC

DATASHEET

Entrez Gene: 2833

Swiss Prot: P49682

Source: Recombinant human CXCR3 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 1-53/368

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011].

Sequence: 1-53/368

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100µg, 500µg, 20µg

Applications: Others

Predicted Molecular Weight: 24

Cross Reactive Species: Others

For research use only. Not intended for diagnostic or therapeutic use.