bs-42376P

DATASHEET

Entrez Gene: 1075

Swiss Prot: P53634

Source: Recombinant human DPP1 protein is expressed in E.coli with N-GST. It contains the amino acid sequence of 25-134/463

Storage Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea

Storage: The product should be stored at -70°C or -20°C.

Background:

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Size: 100ug,500ug

Applications: Others()

Mol. Wt.: 40.3

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.