bs-42407P

DATASHEET

Entrez Gene: 1374

Swiss Prot: P50416

Source: Recombinant human CPT1A protein is expressed in E.coliwith N-His. It contains the amino acid sequence of 421-745/773

Storage Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea

Storage: The product should be stored at -70°C or -20°C.

Background:

The mitochondrial oxidation of long-chain fatty acids is nitiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Sequence: 421-745/773

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 39.2

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.