bs-42429P

DATASHEET

Entrez Gene: 6597

Swiss Prot: P51532

Source: Recombinant Human SMARCA4 Protein in E.coli with N-GST&C-His. It contains the amino acid sequence of 207-298/1647

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Alternatively spliced transcripts have been found for this gene, but their full-length natures have not been determined.

Sequence: 207-298/1647

Size: 100µg, 500µg, 20µg

Applications: Others

Mol. Wt.: 37.4

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.