bs-42433P

DATASHEET

Entrez Gene: 1103

Swiss Prot: P28329

Source: Recombinant human CHAT protein in E.coli with N-His. It contains the amino acid sequence of 399-748/748

Storage Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010].

Sequence: 399-748/748

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 42.8

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.