bs-42443P

DATASHEET

Entrez Gene: 154

Swiss Prot: P07550

Source: Recombinant human ADRB2 protein in E.coli with C-His. It contains the amino acid sequence of 302-413/413

Storage Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.

Sequence: 302-413/413

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 14.6

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.