bs-42444P

DATASHEET

Entrez Gene: 7080

Swiss Prot: P43699

Source: Recombinant human NKX2-1 protein is expressed in E.coli with C-His. It contains the amino acid sequence of 1-371/371

Storage Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Apr 2011]

Size: 100ug,500ug

Applications: Others()

Mol. Wt.: 40.5

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.