bs-42445P

DATASHEET

Entrez Gene: 1280

Swiss Prot: P02458

Source: Recombinant human COL2A1 protein in E.coli with N-GST&C-His. It contains the amino acid sequence of 1220-1282/1487

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]

Sequence: 1220-1282/1487

Size: 100µg, 500µg, 20µg

Applications: Others

Mol. Wt.: 36.3

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.