bs-42449P

DATASHEET

Entrez Gene: 1525

Swiss Prot: P78310

Source: Recombinant human CXADR Protein in E.coli with N-His. It contains the amino acid sequence of 20-237/365

Storage Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

Coxsackie and adenovirus receptor (CAR), also known as CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity. It is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.It is proposed to function as a homophilic cell adhesion molecule and recruits MPDZ to intercellular contact sites. CAR is probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN) through adhesive interactions with AMICA1/JAML located in the plasma membrane of PMN.

Sequence: 20-237/365

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 27.7

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.