bs-42459P

DATASHEET

Entrez Gene: 4316

Swiss Prot: P09237

Source: Recombinant human MMP7 protein in E.coli with N-GST&C-His. It contains the amino acid sequence of 95-267/267

Storage Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Sequence: 95-267/267

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 48.6

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.