bs-42518P

DATASHEET

Entrez Gene: 4609

Swiss Prot: P01106

Source: Recombinant human MYC protein is expressed in E.coli with N-His. It contains the amino acid sequence of 16-454/454

Storage Buffer: 0.01M TBS(pH7.4)

Storage: Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.

Background:

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].

Size: 100ug, 500ug

Applications: Others(N/A)

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.