bs-4252R-FITC [Conjugated Primary Antibody]
SCNN1B Polyclonal Antibody, FITC Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: SCNN1B

Immunogen Range: 401-500/685


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6338

Swiss Prot: P51168

Source: KLH conjugated synthetic peptide derived from human SCNN1B

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 73


Predicted Cross Reactive Species: Human
Mouse
Rat
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Ay?e ?ak?r Gndo?du. et al. Impact of 5'-AMP-activated protein kinase (AMPK) on Epithelial Sodium Channels (ENaCs) in human sperm. TISSUE CELL. 2022 Aug;:101896Read more>>
  • Ay?e ?ak?r Gndo?du. et al. Resveratrol downregulates ENaCs through the activation of AMPK in human colon cancer cells. TISSUE CELL. 2023 Mar;:102071Read more>>
VALIDATION IMAGES