DATASHEET
Host:
Rabbit
Target Protein:
cIAP1
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
329
Source:
KLH conjugated synthetic peptide derived from human cIAP1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C for 12 months.
Background:
Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
PRODUCT SPECIFIC PUBLICATIONS
- Xuan et al. Short?term vagus nerve stimulation reduces myocardial apoptosis by downregulating microRNA?205 in rats with chronic heart failure. (2017) Mol.Med.Rep. 16:5847-5854Read more>>
- Sun et al. Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer. (2015) J.Bioenerg.Biomembr. 47:319-29Read more>>
- He Shanqing. et al. Dapagliflozin Protects Methamphetamine-Induced Cardiomyopathy by Alleviating Mitochondrial Damage and Reducing Cardiac Function Decline in a Mouse Model. FRONT PHARMACOL. 2022 Jul;0:2578Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human colon carcinoma labeled with Rabbit Anti cIAP1/RNF48 Polyclonal Antibody, Unconjugated (bs-4262R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Lane 1: Mouse Testis tissue lysates; Lane 2: Rat Testis tissue lysates probed with cIAP1 Polyclonal Antibody, Unconjugated (bs-4262R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.