bs-4298R [Primary Antibody]
CD74 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD74

Immunogen Range: 201-296/296


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 972

Swiss Prot: P04233

Source: KLH conjugated synthetic peptide derived from human HLA class II histocompatibility antigen gamma chain

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 29


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Dog
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Li TF et al. Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastoma.Biomaterials. 2018 Oct;181:35-52.Read more>>
  • Nan Hou. et al. Tissue-engineered esophagus: recellular esophageal extracellular matrix based on perfusion-decellularized technique and mesenchymal stem cells. Biomed Mater. 2021 AugRead more>>
  • Qiang Liu. et al. F_box and WD repeat_containing protein7 ameliorates angiotensinII_induced myocardial hypertrophic injury via the mTOR_mediated autophagy pathway. EXP THER MED. 2022 Jul;24(1):1-1Read more>>
  • Lee Yi-Mei. et al. Genomic and Transcriptomic Landscape of an Oral Squamous Cell Carcinoma Mouse Model for Immunotherapy. CANCER IMMUNOL RES. 2023 SepRead more>>
  • Sha Liu. et al. L-Theanine alleviates heat stress through modulation of gut microbiota and immunity. J SCI FOOD AGR. 2023 NovRead more>>
VALIDATION IMAGES

Formalin-fixed human pancreatic cancer tissue labeled with Anti-HLA DMβ Polyclonal Antibody, Unconjugated (bs-4298R) at 1:200 followed by conjugation to the secondary antibody and DAB staining