bs-43018P

DATASHEET

Entrez Gene: 348

Swiss Prot: P02649

Source: Recombinant human Apolipoprotein E protein, C-His (HEK293) protein is expressed in HEK293 with C-His. It contains the amino acid sequence of 19-317/317.

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.

Sequence: 19-317/317

Size: 100µg, 500µg, 20µg

Applications: ELISA

Mol. Wt.: 38

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.