bs-43030P
[Protein]
Recombinant mouse CD40L protein, N-His (HEK293)
DATASHEET
Entrez Gene: 21947
Swiss Prot: P27548
Source: Recombinant mouse CD40L protein, N-His (HEK293) protein is expressed in HEK293 with N-His. It contains the amino acid sequence of 112-260/260.
Storage Buffer: 0.01M TBS(pH7.4)
Storage: The product should be stored at -70°C or -20°C.
Background:
CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.
Size: 100ug,500ug
Applications: ELISA()
Mol. Wt.: 20
Species: Others
For research use only. Not intended for diagnostic or therapeutic use.