bs-43082P-Biotin

DATASHEET

Entrez Gene: 7252

Swiss Prot: P01215 (alpha chain) & P01222 (beta chain)

Source: Recombinant human TSH Alpha/Beta Heterodimer protein is expressed in HEK293 cell with C-His.It contains the amino acid sequence of 25-116/116 (Alpha chain) & 21-138/138 (Beta chain)

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Sequence: 25-116/116 (Alpha chain) & 21-138/138 (Beta chain)

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µg, 500µg, 20µg

Applications: Others

Predicted Molecular Weight: 12.2

Cross Reactive Species: Others

For research use only. Not intended for diagnostic or therapeutic use.