bs-43087P

DATASHEET

Entrez Gene: 3596

Swiss Prot: P35225

Source: Recombinant human IL-13 protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 21-132/132

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]

Sequence: 21-132/132

Size: 100µg, 500µg, 20µg

Applications: Others

Mol. Wt.: 14.3

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.