bs-43146P-Biotin

DATASHEET

Entrez Gene: 5972

Swiss Prot: P00797

Source: Recombinant human Renin protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 24-406/406

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008].

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ug,500ug,20ug

Applications: Others()

Mol. Wt.: 44.4

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.