bs-43156P-APC

DATASHEET

Entrez Gene: 43740568

Swiss Prot: P0DTC2

Source: Recombinant SARS-Cov-2 Spike RBD protein (BA.5/Omicron) is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 319-537/1273

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.

Sequence: 319-537/1273

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100µg, 500µg, 20µg

Applications: Others

Predicted Molecular Weight: 26.8

Cross Reactive Species: Others

For research use only. Not intended for diagnostic or therapeutic use.