bs-43161P-Biotin

DATASHEET

Entrez Gene: 3133

Swiss Prot: P13747

Source: Recombinant human HLA-E & Beta-2-MG Heterodimer protein is expressed in HEK293 cell with His&Avi . It contains the amino acid sequence of 22-305/358

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Sequence: 22-305/358

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µg, 500µg, 20µg

Applications: Others

Predicted Molecular Weight: 35.4

Cross Reactive Species: Others

For research use only. Not intended for diagnostic or therapeutic use.