bs-43523P
[Protein]
Recombinant human TGFBR2 protein, C-hFc (HEK293)
DATASHEET
Entrez Gene: 7048
Swiss Prot: P37173
Source: Recombinant human TGFBR2 protein, C-hFc (HEK293) protein is expressed in HEK293 with C-hFc. It contains the amino acid sequence of 23-159/567.
Storage Buffer: 0.01M TBS(pH7.4)
Storage: The product should be stored at -70°C or -20°C.
Background:
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Size: 100ug,500ug
Applications: ELISA()
Mol. Wt.: 44
Species: Others
For research use only. Not intended for diagnostic or therapeutic use.