bs-43555P-Biotin

DATASHEET

Entrez Gene: 10457

Swiss Prot: Q14956

Source: Recombinant human GPNMB protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 23-486/572

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Sequence: 23-486/572

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µg, 500µg, 20µg

Applications: Others

Predicted Molecular Weight: 19.4

Cross Reactive Species: Others

For research use only. Not intended for diagnostic or therapeutic use.