bs-43608P

DATASHEET

Entrez Gene: 8792

Swiss Prot: Q9Y6Q6

Source: Recombinant human RANK protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 30-212/616

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]

Sequence: 30-212/616

Size: 100µg, 500µg, 20µg

Applications: Others

Mol. Wt.: 21.2

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.