bs-43693P

DATASHEET

Entrez Gene: 16409

Swiss Prot: P05555

Source: Recombinant mouse CD11b protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 17-1105/1153

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Sequence: 17-1105/1153

Size: 100µg, 500µg, 20µg

Applications: Others

Mol. Wt.: 122.8

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.