bs-43712P-APC

DATASHEET

Entrez Gene: 968

Swiss Prot: P34810

Source: Recombinant human CD68 protein in HEK293 with C-His. It contains the amino acid sequence of 22-319/354

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100ug,500ug,20ug

Applications: Others()

Mol. Wt.: 33.6

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.