bs-43823P

DATASHEET

Entrez Gene: 939

Swiss Prot: P26842

Source: Recombinant human CD27 protein is expressed in CHO cell with C-His. It contains the amino acid sequence of 21-192/260

Storage Buffer: 0.01M TBS(pH7.4)

Storage: Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Size: 100ug, 500ug

Applications: Others(N/A)

Mol. Wt.: 21.3 kDa

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.