DATASHEET
Swiss Prot:
EPI2224971
Source:
Recombinant Influenza A virus H1N1 (A/Wisconsin/67/2022)/(A/Victoria/2570/2019)/(A/Wisconsin/588/2019) Nucleoprotein is expressed in E.coli withC-His. It contains the amino acid sequence of 1-498/498
Storage Buffer:
0.01M TBS(pH7.4)
Storage:
The product should be stored at -70°C or -20°C.
Background:
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral proteins. The nucleoprotein forms large, RNA-bound, helical filaments and acts as a scaffold for additional viral proteins.