bs-46002P [Protein]
Recombinant Human ACE2
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DATASHEET

Swiss Prot: Q9BYF1

Source: Recombinant Human ACE2 protein is expressed in HEK293 with Fc-Avi. It contains the amino acid sequence of Gln18- Ser740.

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

"ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. "

Endotoxin: Less than 0.5EU per ug by the LAL method.

Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC

Sequence: Gln18- Ser740

Expression: HEK293

Tag: Fc-Avi

Size: 1mg,100ug

Applications: WB()
ELISA()
HPLC()

Mol. Wt.: 111.2


Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Recombinant human ACE2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.




The purity of human ACE2 is greater than 95% as determined by SEC-HPLC.




Immobilized biotinylated n-COV S1, His Tag at 1ug/ml (100ul/Well). Dose response curve for ACE2, Fc tag with the EC50 of 81 ng/ml determined by ELISA.