bs-46110P-APC

DATASHEET

Swiss Prot: Q9BYF1

Source: Recombinant Human ACE2 Protein protein is expressed in Mammalian cells with C-His. It contains the amino acid sequence of Met1-Ser740.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, and heart, in the colon, small intestine, and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor, don‚Äôt inhibit ACE-2 activity. ACE-2 may play an essential role in regulating heart function.

Sequence: Met1-Ser740

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100µg, 500µg, 20µg

Applications: WB
ELISA

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.