bs-4720R-Biotin [Conjugated Primary Antibody]
GDF9 Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: GDF9

Immunogen Range: 301-400/454


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2661

Swiss Prot: O60383

Source: KLH conjugated synthetic peptide derived from human GDF9

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)

Predicted Molecular Weight: 15


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Sheep
Pig
Horse
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Pinar Kacamak. et al. The Effect of Isotretinoin on Oocyte Maturation in Adolescent Female Rats. Gynecol Obstet Inves. 2020;85(4):327-335Read more>>
  • Huihui Wang. et al. Regulation of GDF9 and CDKN1B expression in Tibetan sheep testes during different stages of maturity. Gene Expr Patterns. 2021 Nov;:119218Read more>>
  • F?nd?k Damla Gl. et al. Decreased growth differentiation factor 9, bone morphogenetic protein 15, and forkhead box O3a expressions in the ovary via ulipristal acetate. Revista da Associacao Medica Brasileira. 2023 Aug;69:e20230381Read more>>
VALIDATION IMAGES