bs-4727R [Primary Antibody]
MRC1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: MRC1

Immunogen Range: 210-260/1456

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4360

Swiss Prot: P22897

Source: KLH conjugated synthetic peptide derived from human MRC1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Condition: Store at -20°C for 12 months.

Background: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Karmouty-Quintana, Harry, et al. "Deletion of ADORA2B from myeloid cells dampens lung fibrosis and pulmonary hypertension." The FASEB Journal (2014): fj-14.Read more>>
  • Das, Anusuya, et al. "Bioactive lipid coating of bone allografts directs engraftment and fate determination of bone marrow-derived cells in rat GFP chimeras." Biomaterials (2015).Read more>>
  • Azad, Abul K., et al. "γ-Tilmanocept, a New Radiopharmaceutical Tracer for Cancer Sentinel Lymph Nodes, Binds to the Mannose Receptor (CD206)." The Journal of Immunology (2015): 1402005.Read more>>
  • Locatelli, Luigi, et al. "Macrophage recruitment by fibrocystin‐defective biliary epithelial cells promotes portal fibrosis in congenital hepatic fibrosis."Hepatology (2016).Read more>>
  • Struecker, B., et al. "Implantation of a Tissue-Engineered Neo-Bile Duct in Domestic Pigs." European Surgical Research 56.1-2 (2015): 61-75.Read more>>
  • Zhu, Dan, et al. "M2 Macrophage Transplantation Ameliorates Cognitive Dysfunction in Amyloid-β-Treated Rats Through Regulation of Microglial Polarization." Journal of Alzheimers Disease: 1-13.Read more>>
  • Blomgran, Parmis, et al. "A possible link between loading, inflammation and healing: Immune cell populations during tendon healing in the rat." Scientific Reports 6 (2016): 29824.Read more>>
  • Nakai et al. IL-17A induces heterogeneous macrophages, and it does not alter the effects of lipopolysaccharides on macrophage activation in the skin of mice. (2017) Sci.Rep. 7:12473Read more>>
  • Nishikawa,et al.Highly Dispersible and Bioavailable Curcumin but not Native Curcumin Induces Brown-Like Adipocyte Formation in Mice.(2018) Molecular Nutrition & Food Research. 62:.Read more>>
  • White,et al.GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling.(2018) Endocrine-Related Cancer. 25:453-469.Read more>>
  • Shi F et al. Heat injured stromal cells-derived exosomal EGFR enhances prostatic wound healing afterthulium laser resection through EMT and NF-κB signaling. Prostate. 2019 May 24. Read more>>
  • Ma R et al. Exploring the interactions between engineered nanomaterials and immune cells at 3D Nano-bio interfaces to discover potent Nano-adjuvants. Nanomedicine. 2019 Jun 18;21:102037. Read more>>
  • Xie W et al. Dose Dependent Modulation of Bioactive Glasses Particles on Macrophage and Diabetic Wound Healing. Journal of Materials Chemistry B. 2018.Read more>>
  • Žaloudíková M et al. The effect of exposure to hypoxia on superoxide formation by alveolar macrophages is indirect. Life Sci. 2019 Sep 10;236:116864.Read more>>
  • Nishikawa S et al. Co-Administration of Curcumin and Artepillin C Induces Development of Brown-Like Adipocytes in Association with Local Norepinephrine Production by Alternatively Activated Macrophages in Mice. J Nutr Sci Vitaminol (Tokyo). 2019;65(4):328-334. Read more>>
  • Shao N et al. A Multi‐Functional Silicon Nanoparticle Designed for Enhanced Osteoblast Calcification and Related Combination Therapy. Macromol Biosci. 2019 Nov 10:e1900255. Read more>>
  • Jiang L et al. Sonodynamic Therapy in Atherosclerosis by Curcumin Nanosuspensions: Preparation design, Efficacy Evaluation, and Mechanisms Analysis. Eur J Pharm Biopharm. 2020 Jan;146:101-110.Read more>>
  • Zhan Q et al. Structural characterization and immunomodulatory activity of a novel acid polysaccharide isolated from the pulp of Rosa laevigata Michx fruit. Int J Biol Macromol. 2019 Nov 12. pii: S0141-8130(19)37108-9.Read more>>
  • Liu J et al. Polychlorinated biphenyl quinone promotes macrophage polarization to CD163+ cells through Nrf2 signaling pathway. Environmental Pollution,2019, 113587. Read more>>
  • Shao N et al. A Multi‐Functional Silicon Nanoparticle Designed for Enhanced Osteoblast Calcification and Related Combination Therapy. Macromol Biosci. 2019 Nov 10:e1900255. Read more>>
  • Liu S et al. Absorbable Thioether Grafted Hyaluronic Acid Nanofibrous Hydrogel for Synergistic Modulation of Inflammation Microenvironment to Accelerate Chronic Diabetic Wound Healing. Adv Healthc Mater. 2020 Apr 27:e2000198.Read more>>