Host: Rabbit

Target Protein: Hepatitis C Virus RNA-directed RNA polymerase

Immunogen Range: 2501-2600/3010

Clonality: Polyclonal

Isotype: IgG

Source: KLH conjugated synthetic peptide derived from Hepatitis C Virus RNA-directed RNA polymerase

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Condition: Store at -20°C for 12 months..

Background: The RNA directed RNA polymerase is also known as non-structural protein NS5B. NS5B is a 65 kDa protein that resembles other viral RNA polymerases. Hepatitis C virus (HCV) replication is thought to occur in membrane bound replication complexes. These complexes transcribe the positive strand and the resulting minus strand is used as a template for the synthesis of genomic RNA. There are two viral proteins involved in the reaction, NS3 and NS5B