bs-4906R-Biotin [Conjugated Primary Antibody]
SLC40A1 Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: SLC40A1

Immunogen Range: 331-430/571


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 30061

Swiss Prot: Q9NP59

Source: KLH conjugated synthetic peptide derived from human SLC40A1/FPN1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)

Predicted Molecular Weight: 63


Cross Reactive Species: Human
Mouse
Chicken

Predicted Cross Reactive Species: Rat
Dog
Pig
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Rychtarcikova, Zuzana, et al. "Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism." Oncotarget (2016).Read more>>
  • Zhang, L. Y., et al. "Effect of iron source on iron absorption and gene expression of iron transporters in the ligated duodenal loops of broilers." Journal of Animal Science (2017).Read more>>
  • Calatrava-Ferreras et al. Liver Growth Factor (LGF) Upregulates Frataxin Protein Expression and Reduces Oxidative Stress in Friedreich's Ataxia Transgenic Mice. (2016) Int.J.Mol.Sci. 17 Read more>>
  • Wang,et al.Vasoactive intestinal peptide inhibits airway smooth muscle cell proliferation in a mouse model of asthma via the ERK1/2 signaling pathway.(2018) Experimental Cell Research. 364:168-174.Read more>>
  • Zixuan Liu. et al. Tetrachlorobenzoquinone exposure triggers ferroptosis contributing to its neurotoxicity. Chemosphere. 2021 Feb;264:128413Read more>>
  • Zixuan Liu. et al. Fostered Nrf2 expression antagonizes iron overload and glutathione depletion to promote resistance of neuron-like cells to ferroptosis. Toxicol Appl Pharm. 2020 Nov;407:115241Read more>>
  • Qingxin Song. et al. Temozolomide Drives Ferroptosis via a DMT1-Dependent Pathway in Glioblastoma Cells. Yonsei Med J. 2021 Sep 1; 62(9): 843C849Read more>>
  • Ma, Sai. et al. Canagliflozin mitigates ferroptosis and ameliorates heart failure in rats with preserved ejection fraction. N-S ARCH PHARMACOL. 2022 Apr;:1-18Read more>>
  • Huang Bin. et al. Dapagliflozin Ameliorates Renal Tubular Ferroptosis in Diabetes via SLC40A1 Stabilization. OXID MED CELL LONGEV. 2022;2022:9735555Read more>>
  • Xu Zhu. et al. Brusatol induces ferroptosis in oesophageal squamous cell carcinoma by repressing GSH synthesis and increasing the labile iron pool via inhibition of the NRF2 pathway. BIOMED PHARMACOTHER. 2023 Nov;167:115567Read more>>
VALIDATION IMAGES