bs-5013R [Primary Antibody]
ABCG5 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: ABCG5

Immunogen Range: 251-350/651


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 64240

Swiss Prot: Q9H222

Source: KLH conjugated synthetic peptide derived from human ABCG5

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 72


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wang, Shuling, et al. "Chronic unpredictable mild stress combined with a high-fat diets aggravates atherosclerosis in rats." Lipids in Health and Disease 13.1 (2014): 77.Read more>>
  • Zhong, Chun-Yan, et al. "Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice." Scientific Reports 5 (2015).Read more>>
  • Ding, Lin, et al. "Eicosapentaenoic acid-enriched phospholipids improve atherosclerosis by mediating cholesterol metabolism." Journal of Functional Foods 32 (2017): 90-97.Read more>>
  • Gao et al. Acute stress show great influences on liver function and the expression of hepatic genes associated with lipid metabolism in rats. (2013) Lipids.Health.Dis. 12:118Read more>>
  • Huang et al. Effects of mulberry leaf on experimental hyperlipidemia rats induced by high-fat diet. (2018) Exp.Ther.Med. 16:547-556Read more>>
  • Zhang L et al. Eicosapentaenoic acid in the form of phospholipid exerts superior anti-atherosclerosis effects than its triglyceride form in ApoE-/-mice. Food & Function. 2019  Read more>>
  • Yan R et al. PM2. 5 exposure induces age-dependent hepatic lipid metabolism disorder in female mice. journal of environmental science.2019.Read more>>
  • Jean Baptiste Nyandwi. et al. Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice. Biomolecules. 2021 Oct;11(10):147Read more>>
  • Huiming Hu. et al. The Hypolipidemic Effect of Hawthorn Leaf Flavonoids through Modulating Lipid Metabolism and Gut Microbiota in Hyperlipidemic Rats.. EVID-BASED COMPL ALT. 2022 Nov;2022:3033311-3033311Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rat liver labeled with Anti-ABCG5 Polyclonal Antibody, Unconjugated (bs-5013R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.