bs-51073R

DATASHEET

Host: Rabbit

Target Protein: PAPD5

Clonality: Polyclonal

Isotype: Not determined

Entrez Gene: 64282

Swiss Prot: Q8NDF8

Source: Polyclonal antibody raised in rabbit against human PAPD5 (PAP associated domain containing 5), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein

Purification: Whole antiserum from rabbit containing 0.05% azide

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.

Size: 100ul

Concentration: Not Determined

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.