bs-5226R-A350

DATASHEET

Host: Rabbit

Target Protein: BRIP1 Ser990

Specificity: This phosphorylation site is homologous to that of Ser921 in Bovine.

Modification Site: Ser990

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 83990

Swiss Prot: Q9BX63

Source: KLH conjugated synthetic phosphopeptide derived from human BRIP1 around the phosphorylation site of Ser990

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

Conjugation: ALEXA FLUOR® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 141

Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Cow
Sheep

For research use only. Not intended for diagnostic or therapeutic use.