bs-55002R

DATASHEET

Host: Rabbit

Target Protein: ADRBK1

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 156

Swiss Prot: P25098

Source: Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human ADRBK1 (NP_001610.2).

Purification: purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IHC(1:50-200)
IHC-P(1:200-400)

Predicted Molecular Weight: 79kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.