bs-55024R-BF594

DATASHEET

Host: Rabbit

Target Protein: Beclin 1

Specificity: KO-Validated

Immunogen Range: 181-280/450

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8678

Swiss Prot: Q14457

Source: KLH conjugated synthetic peptide derived from human BECN1

Purification: purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Conjugation: AbBy Fluor-594

Excitation/ Emission: 590nm/617nm

Size: 100ul

Concentration: 1mg/ml

Applications: WB(1:500-1000)
IHC-F(1:400-800)
IF(1:100-500)
IHC-P(1:400-800)

Predicted Molecular Weight: 60 kDa

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Rabbit

For research use only. Not intended for diagnostic or therapeutic use.