bs-55034R

DATASHEET

Host: Rabbit

Target Protein: CAST

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 831

Swiss Prot: P20810

Source: A synthetic peptide corresponding to a sequence within amino acids 550-650 of human CAST (NP_001177371.1).

Purification: purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Size: 100ul

Concentration: Lot Dependent

Applications: WB(1:300-5000)

Predicted Molecular Weight: 63kDa/71- 84kDa

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.